Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents

Figure 20

Segmental arterial mediolysis, reparative phase. The cyan arrow points to a hematoma formed in the mature granulation tissue filling and expanding the adventitial medial tear. Adjacent scattered red cells are gathered at the external elastica (black arrow). The red arrow points to a large dissecting hematoma bordered by an intact external elastica. Part of this dissections is evident in the superior view of the artery, and a beginning dissection appears to be generating near the black arrow. The blue arrow points to foci of outer medial fibrosis (yellow stain). Movat stain ×25.