Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents

<div>Segmental arterial mediolysis injurious phase. Initial phase of mediolysis. The black arrow points to large, and the red arrow to smaller cytoplasmic vacuoles containing nonstaining clear contents (water) distributed in the outer medial muscle. Hematoxylin &amp; eosin ×400 (adapted with permission from Veterinary Pathology 52(6), copyright 2015, Sage Publications Inc.).</div>

International Journal of Vascular Medicine

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Figure 3: Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents 

Figure 3 | Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents 