Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents

<div>Myocardium in segmental arterial mediolysis. Apoptotic bodies composed of well-circumscribed densely eosinophilic cytoplasmic budding fragments are evident dispersed in newly formed granulation tissue composed of fibroblasts and capillaries. Hematoxylin &amp; eosin ×200 (adapted from EC Cardiology 5.7 2018, online publication).</div>

International Journal of Vascular Medicine

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Figure 37

Figure 37: Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents 

Figure 37 | Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents 