Female Sprague Dawley Rats Show Impaired Spatial Memory in the 8-Arm Radial Maze under Dim Blue and Red Light

Table 1

Statistical analysis of the last session 5. Male and female Sprague Dawley rats were tested in a spatial memory task in an 8-arm radial maze under different lighting conditions. The performance of the rats was analyzed at the last training session (five) by a one-way ANOVA with a subsequent Fisher's LSD posthoc test. (Corr %: percentage of correct choices; total errors; RME: reference memory errors; WME: working memory errors; RWME: reference/working memory errors). Values are given as mean ± SEM. Differences between sexes are shown in the last column while differences between light exposure groups are shown within the respective column (*𝑃<.05; ns: not significant). Latency = time/visits.

Treatment	S5 all trails	Male	Female	𝑃
White light	Corr %	66 ± 5	65 ± 6	ns
	Total Errors	2.9 ± 0.7	2.7 ± 0.5	ns
	RME	1.5 ± 0.3	1.5 ± 0.3	ns
	WME	1.1 ± 0.4	1.3 ± 0.3	ns
	RWME	0.3 ± 0.1	0.1 ± 0.1	ns
	Visits	6.9 ± 0.7	6.7 ± 0.5	ns
	Time	238 ± 35	170 ± 18	ns
	Latency	39 ± 7	26 ± 2	ns
Blue light	Corr %	76 ± 5ns	62 ± 5ns	ns
	Total Errors	1.7 ± 0.4ns	3.0 ± 0.5ns	.0487*
	RME	0.9 ± 0.2ns	1.7 ± 0.3ns	.0384*
	WME	0.6 ± 0.2ns	1.0 ± 0.3ns	ns
	RWME	0.2 ± 0.1ns	0.3 ± 0.2ns	ns
	Visits	5.7 ± 0.4ns	7.0 ± 0.5ns	ns
	Time	138 ± 9ns	171 ± 15ns	ns
	Latency	25 ± 1ns	25 ± 2ns	ns
Red light	Corr %	76 ± 5ns	59 ± 5ns	.0251*
	Total Errors	1.9 ± 0.5ns	3.5 ± 0.6ns	.0326*
	RME	1.0 ± 0.3ns	1.8 ± 0.3ns	.0467*
	WME	0.8 ± 0.3ns	1.3 ± 0.3ns	ns
	RWME	0.1 ± 0.1ns	0.4 ± 0.2ns	ns
	Visits	5.9 ± 0.5ns	7.5 ± 0.6ns	.0330*
	Time	142 ± 9ns	178 ± 21ns	ns
	Latency	25 ± 1ns	24 ± 2ns	ns