|
| Study (year), country | Design | AR type | Size (M/F) | Age (years) | Intervention and control | Operating time/day and study period |
|
| Park et al. [34], South Korea | RCT parallel | AR sensitized to HDMs | I: 22 (6/16)
C: 22 (9/13) | I: 35.
C: | I: air purifier with HEPA filter
C: without HEPA filter | 24 hours/day
6 weeks |
| Li et al. [33], China | RCT parallel | AR sensitized to
Artemisa pollen | I: 45 (24/21)
C: 45 (26/19) | I: 35.53
C: 36.11 | I: air purifier with HEPA filter
C: placebo HEPA filter | Continuous
8 weeks (4 weeks for treatment and 4 weeks for observation) |
| Wood et al. [32], USA | RCT parallel | AR sensitized to cat allergen | I: 18 (2/16)
C: 17 (8/9) | I: 36.3
C: 36.4 | I: air cleaner with HEPA filter
C: without HEPA filter | Continuous
3 months |
| Brehler et al. [31], Germany | RCT crossover | AR sensitized to
tree or grass pollen | 44 (23/31) | NI | I: air ventilator with pollen filter
C: placebo filter | Continuous
4 weeks (2 weeks for intervention and 2 weeks for control) |
| Stillerman et al. [35], USA | RCT crossover | PRAC sensitized to dust, mite, dog, or cat | 35 (13/22) | 39.1 | I: PAF pillow with HEPA filter
C: blocked HEPA filter | During sleep (at least 12 of 14 nights)
6 weeks (2-week treatment, 1-week wash out, 2-week treatment, 1-week washout) |
| Antonicelli et al. [16], Italy | RCT crossover | AR sensitized to
D. pteronyssinus and D. farina | 9 (NA) | 16 | I: air cleaner with HEPA filter
C: without filter | 24 hours/day
16 weeks (8 weeks for treatment and 8 weeks for observation) |
| Reisman et al. [17], USA | RCT crossover | Perennial AR
sensitized to HDMs | 32 (12/20) | 27.5 | I: air cleaner with HEPA filter
C: placebo filter | NI
8 weeks (4 weeks for intervention and 4 weeks for control) |
| Kooistra et al. [24], USA | RCT crossover | AR sensitized to
ragweed pollen | 20 (11/9) | NI | I: air cleaner with internal filter
C: no filter | 24 hours/day
8 weeks (4 weeks for intervention and 4 weeks for control) |
|
