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Interdisciplinary Perspectives on Infectious Diseases
Volume 2009, Article ID 195040, 5 pages
Review Article

Chemotherapy of Human African Trypanosomiasis

Department of Biological and Health Sciences, Haskins Laboratory, Pace University, New York, NY 10038, USA

Received 27 March 2009; Accepted 28 April 2009

Academic Editor: Louis M. Weiss

Copyright © 2009 Cyrus J. Bacchi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Human Africa trypanosomiasis is a centuries-old disease which has disrupted sub-Saharan Africa in both physical suffering and economic loss. This article presents an update of classic chemotherapeutic agents, in use for >50 years and the recent development of promising non-toxic combination chemotherapy suitable for use in rural clinics.