Interdisciplinary Perspectives on Infectious Diseases / 2009 / Article / Tab 1

Review Article

The Impact of HIV and Malaria Coinfection: What Is Known and Suggested Venues for Further Study

Table 1

Effects of coinfection with HIV and malaria.

Type of InteractionPregnant womenChildrenAdult men and nonpregnant women

Effect of HIV on malaria
• ↑ Risk of infection+?+
• ↑ Parasite density+?+

Effect of malaria on HIV
• ↑ Viral load+?+
• ↑ Transmission?+?
(Data on vertical transmission to the fetus is contradictory)(Through transfusion of unscreened blood for anemia)(No definitive data, although ↑ viral load has previously been shown to correlate with ↑ sexual transmission)

Effects of dual infection
• ↑ Severity of illness+++
• ↑ Frequency and severity of anemia+++
• ↑ Frequency of low birth weight+N/AN/A

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