Interdisciplinary Perspectives on Infectious Diseases / 2009 / Article / Fig 12

Review Article

Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs

Figure 12

DIC microscopy (left panel) and immunofluorescence microcospy (right panel) of L. amazonensis promastigotes control (a)-(b) and treated with ER-119884 (c)-(d). The labeling corresponds to the cytoskeleton constituted mainly by tubulin, revelead here by using of an Alexa 488-labeled secondary antibody. The black arrow in DIC image corresponds to the cell body which sometimes appeared changed and rounded as compared to the control parasites, while the white arrows point to several tubulin clusters that accumulated in the cytosol after treatment. All images are reproduced with permission from [37] American Society for Microbiology. Bars, m.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.