Interdisciplinary Perspectives on Infectious Diseases / 2009 / Article / Fig 8

Review Article

Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs

Figure 8

Promastigotes treated with quinuclidine and azasterol, respectively, showing the presence of structures related with autophagy such as a large vacuole containing many membrane profiles ((a), arrowheads), and a myelin-like figures involving part of the cytosol ((b), arrowhead). Star indicates the presence of a possible contractile vacuole near the flagellar pocket. A, autophagosome; F, flagellum; K, kinetoplast; M, mitochondrion; N, nucleus. (a) This image is reproduced with permission from [66] Elsevier. Bars, m.

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