B Cell IgD Deletion Prevents Alveolar Bone Loss Following Murine Oral Infection
P gingivalis-infected IgD deficient mice had a lower proportion of activated B cells than infected immune normal BALB/cJ mice. (a) The total B cell population: the percentage of total viable CD1 B cells in the sham-infected mice were the same in both strains (). In neither mouse strain was the total B cell population changed by P. gingivalis infection (, infected compared to sham-infected mice). (b) Activated B cell population: the proportion of activated B cells in infected IgD deficient mice were significantly lower than in infected BALB/cJ mice, (, indicated by *) ; 42 days postinfection.
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