B Cell IgD Deletion Prevents Alveolar Bone Loss Following Murine Oral Infection
P. gingivalis-infection increased the proportion of CD4+ T cells and activated them in immune normal BALB/cJ mice but not in IgD deficient mice. (a) Total CD T cell population: in immune normal BALB/cJ mice the percentage of total viable CD T cells were higher in infected than in sham-infected () but in IgD deficient mice the percentage was unchanged by infection (). (b) Activated CD T cells: In BALB/cJ mice the proportion of activated CD CD69+ T cells were higher in P. gingivalis-infected than in sham-infected mice () but activation was not increased by infection in IgD deficient mice (). .
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