Porphyromonas gingivalis and Treponema denticola Mixed Microbial Infection in a Rat Model of Periodontal Disease
Figure 1
Serum IgG and IgG subclass (IgG1, IgG2a, IgG2b, IgGc) antibody levels. Serum IgG antibody levels in serum from rats [collected at end of a 7 weeks (a and b) and 12 weeks (c–f) infection] following mono infection () or mixed infection (). The graphs show the results for IgG and IgG subclass antibody reactive with each of the two species of bacteria. The bars indicate the mean antibody concentrations in serum from rats orally infected with the individual bacteria or with mixed bacteria or from sham-infected control rats. The error bars indicate one standard deviation from the mean. An asterisk indicates that a value is significantly different () than the value for sham-infected control rats or for antibody in serum from rats infected with a different microorganism. Pg, P. gingivalis; Td, T. denticola; Cont; sham-infected control.
