Interdisciplinary Perspectives on Infectious Diseases

Research Article

Porphyromonas gingivalis and Treponema denticola Mixed Microbial Infection in a Rat Model of Periodontal Disease

Table 1

Morphometric measurements of horizontal alveolar bone loss (area) on the buccal and palatal surfaces of all molars in rats.


Infection/Groups		Control	P. gingivalis	T. denticola	P. gingivalis + T. denticola

Maxilla 7 Weeks	Buccal	3.2 ± 0.45	3.4 ± 0.47	4.8 ± 0.47	4.3 ± 0.45
Maxilla 7 Weeks	Palatal	5.5 ± 0.47	6.2 ± 0.66	6.5 ± 0.23	7.5 ± 0.77
Mandible 7 Weeks	Buccal	3.7 ± 0.38	4.5 ± 0.51	4.4 ± 0.46	4.8 ± 0.32
Mandible 7 Weeks	Palatal	6.5 ± 0.54	7.4 ± 0.51	8.0 ± 0.4	8.8 ± 0.8
Maxilla 12 Weeks	Buccal	3.2 ± 0.45	5.1 ± 0.88	5.8 ± 0.91	5.4 ± 0.48
Maxilla 12 Weeks	Palatal	5.6 ± 0.63	7.4 ± 0.98	7.7 ± 0.74	8.5 ± 0.64
Mandible 12 Weeks	Buccal	3.5 ± 0.25	3.6 ± 0.64	4.7 ± 0.58	4.2 ± 0.69
Mandible 12 Weeks	Palatal	6.6 ± 0.34	7.6 ± 0.80	8.7 ± 0.51	9.3 ± 0.33

Mean value and standard deviation from six mice per each group measured using AxioVision line tool software as described in methods section. Significantly more than sham-infected control group (). Significantly more than sham-infected control group (). Significantly more than P. gingivalis infected group (). Significantly more than P. gingivalis infected group (). Significantly more than T. denticola infected group ().