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Interdisciplinary Perspectives on Infectious Diseases
Volume 2011 (2011), Article ID 291513, 9 pages
Research Article

Quantitative Evaluation of Bacteria Adherent and in Biofilm on Single-Wall Carbon Nanotube-Coated Surfaces

1Dipartimento di Sanità Pubblica e Malattie Infettive, Sapienza-Università di Roma, Piazzale A. Moro 5, 00185 Roma, Italy
2Centro di Ricerca per le Nanotecnologie Applicate all'Ingegneria, CNIS, Sapienza-Università di Roma, Piazzale A. Moro 5, 00185 Roma, Italy
3Dipartimento di Scienze di Base e Applicate per l'Ingegneria, Sapienza-Università di Roma, Via A. Scarpa 16, 00161 Roma, Italy
4Dipartimento di Scienze e Tecnologie Chimiche, MINASlab, INFN, Università di Roma Tor Vergata, Via della Ricerca Scientifica, 00133 Roma, Italy

Received 13 January 2011; Revised 7 July 2011; Accepted 11 August 2011

Academic Editor: Elizabeth Bukusi

Copyright © 2011 Fabrizio Pantanella et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Biofilm is a common bacterial lifestyle, and it plays a crucial role in human health, causing biofilm-mediated infections. Recently, to counteract biofilm development, new nano-structured biomaterials have been proposed. However, data about the antibacterial properties of nano-structured surfaces are fragmentary and controversial, and, in particular, the susceptibility of nano-structured materials to colonization and biofilm formation by bacterial pathogens has not been yet thoroughly considered. Here, the ability of the pathogenic Streptococcus mutans and Pseudomonas aeruginosa to adhere and form biofilm on surfaces coated with single-wall carbon nanotubes (SWCNTs) was analyzed. Our results showed that the surfaces of SWCNTs-coated glass beads (SWCNTs-GBs) were colonized at the same extent of uncoated GBs both by S. mutans and P. aeruginosa. In conclusion, our results demonstrate that single wall SWCNTs-coated surfaces are not suitable to counteract bacterial adhesion and biofilm development.