Clinical Study

Factors Associated with Late Presentation of HIV and Estimation of Antiretroviral Treatment Need according to CD4 Lymphocyte Count in a Resource-Limited Setting: Data from an HIV Cohort Study in India

Table 2

Factors associated with late HIV presentation stratified by gender.

WomenMen
CD4 countCD4 count <350/mm3CD4 countCD4 count <350/mm3
Median (IQR)Proportion (%)aOR95% CIMedian (IQR)Proportion (%)aOR95% CI

Age (years)
 15 to 24373 (223–548)464/999 (46.4)0.58***(0.48–0.71)249 (128–414)226/336 (67.3)0.71*(0.54–0.94)
 25 to 34271 (133–447)744/1213 (61.3)1Reference185 (94–353)1122/1512 (74.2)1Reference
 35 to 44190 (95–355)348/473 (73.6)1.64***(1.26–2.12)159 (79–287)804/999 (80.5)1.47***(1.20–1.80)
 ≥45160 (84–293)156/191 (81.7)2.48***(1.62–3.79)161 (87–302)406/492 (82.5)1.67***(1.26–2.20)

Marital status
 Single217 (105–429)18/27 (66.7)1.73(0.62–4.78)197 (105–353)241/328 (73.5)1.09(0.81–1.48)
 Married315 (162–510)941/1705 (55.2)1Reference180 (91–332)1987/2597 (76.5)1Reference
 Separated-divorced225 (111–435)134/200 (67)1.44*(1.01–2.05)139 (82–293)110/134 (82.1)1.41(0.88–2.25)
 Widow241 (118–408)581/881 (65.9)1.24*(1.01–1.53)156 (80–280)161/202 (79.7)1(0.69–1.46)

Education
 Higher355 (166–525)25/54 (46.3)0.50*(0.26–0.96)212 (112–368)119/167 (71.3)0.86(0.57–1.29)
 Secondary367 (197–546)264/567 (46.6)0.58***(0.46–0.73)189 (92–343)804/1065 (75.5)1.02(0.83–1.26)
 Primary325 (170–532)166/307 (54.1)0.79(0.59–1.04)171 (94–315)504/638 (79)1.14(0.90–1.45)
 No education253 (120–428)1219/1884 (64.7)1Reference168 (88–325)1077/1397 (77.1)1Reference

Community
 Other castes294 (134–477)378/641 (59)0.93(0.75–1.16)175 (87–340)674/887 (76)0.93(0.76–1.14)
 Backward castes290 (140–461)842/1414 (59.5)1Reference184 (95–330)1203/1573 (76.5)1Reference
 Scheduled castes266 (126–452)373/603 (61.9)1.06(0.85–1.33)174 (85–313)532/672 (79.2)1.14(0.90–1.43)
 Scheduled tribes303 (168–498)119/218 (54.6)0.77(0.56–1.07)175 (104–379)149/207 (72)0.77(0.55–1.09)

House type
 Owned295 (150–470)773/1321 (58.5)1Reference185 (101–340)1166/1536 (75.9)1Reference
 Rented314 (167–473)513/925 (55.5)0.91(0.75–1.10)197 (101–361)673/910 (74)0.98(0.80–1.20)
 No house200 (90–402)202/292 (69.2)1.50*(1.10–2.04)134 (67–267)323/383 (84.3)1.60**(1.18–2.17)
 Other274 (118–454)59/97 (60.8)1.05(0.67–1.66)135 (80–294)159/201 (79.1)1.39(0.96–2.02)

Monthly income (INRa)
 <1000281 (140–460)715/1204 (59.4)1Reference178 (90–325)942/1223 (77)1Reference
 1001 to 2000287 (154–432)204/339 (60.2)0.98(0.74–1.30)182 (97–325)547/705 (77.6)1.12(0.89–1.42)
 2001 to 3000270 (119–443)71/111 (64)1.25(0.79–1.96)182 (92–369)236/323 (73.1)0.92(0.69–1.24)
 >3000303 (148–458)76/135 (56.3)1(0.65–1.54)183 (89–353)529/707 (74.8)0.93(0.74–1.19)
 Not applicable297 (144–493)489/839 (58.3)1.13(0.86–1.48)160 (89–299)224/280 (80)1.18(0.82–1.69)

Occupation
 Unskilled labourer257 (122–435)932/1472 (63.3)1Reference170 (87–323)947/1219 (77.7)1Reference
 Driver180 (93–330)307/406 (75.6)1.05(0.79–1.40)
 Farmer379 (211–536)40/84 (47.6)0.73(0.44–1.21)161 (86–304)362/454 (79.7)1.19(0.89–1.59)
 Health worker304 (177–551)22/41 (53.7)1.11(0.54–2.30)250 (127–500)5/10 (50)0.4(0.11–1.49)
 Housekeeper336 (176–521)398/752 (52.9)0.91(0.69–1.21)388 (220–594)2/5 (40)0.18(0.03–1.18)
 Weaver319 (226–488)16/30 (53.3)0.91(0.40–2.09)272 (118–426)42/70 (60)0.52*(0.31–0.87)
 Others273 (140–463)220/367 (59.9)1.11(0.85–1.45)193 (98–343)789/1049 (75.2)1(0.80–1.24)
 Unemployed168 (100–356)40/57 (70.2)0.99(0.50–1.98)131 (82–261)49/56 (87.5)2.13(0.89–5.12)

Living near a cityb
 No286 (136–458)966/1610 (60)1Reference171 (87–318)1466/1874 (78.2)1Reference
 Yes286 (138–470)746/1266 (58.9)1(0.84–1.19)189 (97–353)1092/1465 (74.5)0.87(0.73–1.03)

Route of transmission
 Heterosexual291 (140–468)1443/2453 (58.8)1Reference178 (90–326)2446/3174 (77.1)1Reference
 Blood transfusion263 (129–479)43/66 (65.2)1.15(0.61–2.16)191 (92–315)17/22 (77.3)0.93(0.33–2.60)
 Homosexual386 (313–406)2/5 (40)0.36(0.05–2.47)
 Others250 (139–363)14/21 (66.7)1.48(0.42–5.23)214 (102–387)17/24 (70.8)0.7(0.27–1.83)
Alcohol consumption
 Yes282 (153–431)15/20 (75)1.58(0.41–6.07)173 (89–324)1592/2064 (77.1)0.99(0.83–1.19)
 Never288 (140–462)1579/2667 (59.2)1Reference192 (95–345)911/1200 (75.9)1Reference

aIndian Rupees (approximately 1$ = 46 INR in September 2011).
bpopulation >100,000 people.
.