Clinical Study

Utility of Serum Neopterin and Serum IL-2 Receptor Levels to Predict Absolute CD4 T Lymphocyte Count in HIV Infected Cases

Table 1

Demographic and baseline characteristics of the study subjects.

Characteristic Group A
(CD4 < 200)
( )
Group B
(CD4 200–500) ( )
Group C
(CD4 > 500) ( )
HIV positive subjects
( )
Healthy control group
( )

Median (IQR) of age in yrs 32.0 (25–41)32.5 (27–39)33.0 (24–39)32.5 (24–41)31.5 (26–40)
Males/females (No.) 22/1123/1122/1167/3328/14
Marital status
 Married2326227130
 Unmarried657189
 Widowed434113
Risk behaviour
 Heterosexual3029278638
 IVDU*24394
 MSM10230
 Not known01120
Median (IQR) CD4 count (cells/µL)111 (79–154)305 (259–392)580 (524–750)279 (154–482)805 (645–1063)
Median (IQR) of S. neopterin (nmol/L)38.57 (25.7–126.0)22.9 (13.4–40.3)16.24 (10.3–23)25.5 (15.6–39.7)6.3 (4.7–6.8)
Median (IQR) of sIL-2R (pM)96.09 (61.4–139.0)60.85 (40.8–86.8)35.09 (25.2–64.6)63 (42.6–100.1)4.4 (1.9–8.1)
Mean (range) of PVL (copies/mL)145,000
(2436–>750,000)
ND#ND145,000
(2436–>750,000) , group A only
ND

Intravenous drug users.
#ND: not done.