Clinical Study

Utility of Serum Neopterin and Serum IL-2 Receptor Levels to Predict Absolute CD4 T Lymphocyte Count in HIV Infected Cases

Table 2

Change in the level of markers from baseline to followup in the three groups.

MarkerGroup A (CD4 < 200)Group B (200–500)Group C (>500)
Baseline
Median
(IQR)
FU
Median
(IQR)
P valueBaseline
Median
(IQR)
FU
Median
(IQR)
P valueBaseline
Median
(IQR)
FU
Median
(IQR)
P value

CD4 count (cells/µL)111
(79–154)
216 (159–253)0.000305 (259–392)274 (200–406)0.162580 (524–750)487 (383–576)0.008
S. neopterin (nmol/L)38.6
(27.5–128.1)
11.2 (8.13–21)0.0022.9 (13.4–40.3)37.1 (16.6–63.3)0.00316.2 (10.3–23)27.6 (19.2–43.1)0.001
sIL-2R (pM)96.1
(61.4–139.1)
45.5 (26.7–65.2)0.00060.9 (40.9–86.8)77.8 (56.9–98.2)0.01735.1 (25.2–64.6)53.1 (37.5–84.9)0.004