Clinical Study
Utility of Serum Neopterin and Serum IL-2 Receptor Levels to Predict Absolute CD4 T Lymphocyte Count in HIV Infected Cases
Table 4
Measures of validity and roc curve area of neopterin and sIL-2R in relation to the CD4 cell count <200 cells/μL.
| Measures of validity | S. neopterin (95% CI) | sIL-2R (95% CI) |
| Cutoff value | >25.1 nmol/L | >47.1 pM | Sensitivity | 90.9 (95% CI: 70.8–98.9) | 95.5 (95% CI: 77.2–99.9) | Specificity | 67.4 (95% CI: 52.0–80.5) | 60.9 (95% CI: 45.4–74.9) | Positive predictive value | 86.4 (74.5–93.2) | 92.3 (79.1–96.4) | Negative predictive values | 70.0 (61.3–78.8) | 58.7 (49.3–72.8) | ROC curve area | 0.83 (0.71–0.90), | 0.82 (0.71–0.90), |
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