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Interdisciplinary Perspectives on Infectious Diseases
Volume 2013 (2013), Article ID 370769, 5 pages
http://dx.doi.org/10.1155/2013/370769
Review Article

The Importance of IgG Avidity and the Polymerase Chain Reaction in Treating Toxoplasmosis during Pregnancy: Current Knowledge

Department of Obstetrics, Federal University of São Paulo (UNIFESP), Rua Carlos Weber, 956 Apartment, 113 Visage, Vila Leopoldina, 05303-000 São Paulo, SP, Brazil

Received 12 May 2013; Revised 25 August 2013; Accepted 4 September 2013

Academic Editor: Lúcia Galvão

Copyright © 2013 João Bortoletti Filho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A brief report on the nature and epidemiology of T. gondii infection is firstly presented. The importance of the specific IgG avidity test and polymerase chain reaction (PCR) for toxoplasmosis is discussed, along with their significance and importance as auxiliary methods for determining the most likely time for the initial infection by this coccidian and for defining the therapeutic strategy. Lastly, practical comments are made in relation to the classical therapeutic regimens, with special attention to the indications for fetal treatment, when this is necessary.