Interdisciplinary Perspectives on Infectious Diseases / 2013 / Article / Tab 1

Clinical Study

Prospective Trial of a Novel Nomogram to Achieve Updated Vancomycin Trough Concentrations

Table 1

Characteristics of study subjects.

Characteristics Nomogram ( )Traditional ( )P value

Age (yrs)a58 ± 1861 ± 170.040
Actual body weight (kg)a83.6 ± 18.783.9 ± 17.40.873
Ideal body weight (kg)a63.5 ± 10.665.5 ± 11.60.051
Height (in)a66.8 ± 3.967.5 ± 4.30.051
Initial SCr (mg/dL)a0.96 ± 0.311.0 ± 0.380.143
Change in SCr (%)a14 ± 11.615 ± 11.50.389
Intensive care unit admission: n (%)40 (18)57 (23)0.271
Gender: n (% Females)107 (48)105 (42)0.168
Patients stratified by creatinine clearance: n (%)
 ≥100 mL/min79 (35.7)59 (23.4)
 80–99 mL/min27 (12.2)46 (18.3)
 60–79 mL/min53 (24.0)59 (23.4)
 40–59 mL/min42 (19.0)51 (20.2)
 20–39 mL/min20 (9.0)37 (14.7)
 ≤19 mL/min00
Patients stratified by diagnosis: n (%)
 Pneumonia66 (29.9)76 (30.2)
 Cellulitis68 (30.8)72 (28.6)
 Bacteremia32 (14.5)32 (12.7)
 Osteomyelitis11 (5.0)13 (5.2)
 Abscess15 (6.8)11 (4.4)
 Empiric10 (4.5)16 (6.3)
 Urinary tract infection2 (0.9)9 (3.6)
 Respiratory failure3 (1.4)6 (2.4)
 Miscellaneous: endocarditis, meningitis, febrile neutropenia, diverticulitis, and wounds14 (6.3)17 (6.7)

aMean ± standard deviation.
SCr: serum creatinine.

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