Serine Proteases of Malaria Parasite Plasmodium falciparum: Potential as Antimalarial Drug Targets
Figure 1
Role of serine proteases at asexual blood stages (a) and liver stages of Plasmodium falciparum (b). Subtilisin-like proteases are essential for merozoite invasion and egress in blood stages, liver stage schizont development and subsequent liver stage merozoite egress. Rhomboid protease activities are supposed to be involved in invasion of RBC and liver.
