A Comparative Systematic Review of the Optimal CD4 Cell Count Threshold for HIV Treatment Initiation

Table 2

Effect measure and referent group of studies reviewed.

Author	Reference (cells/𝜇L)	>500 cells/μL HR	<500 HR cells/μL HR; (350–500 cells/μL, *450 cells/μL)
García et al. [9]	<200	0.192 (0.047–0.79)	0.238 (0.086–0.662)
Van Griensven and Thai [10]	<200	0.32 (0.13–0.79)	0.23 (0.10–0.53)
Van Lelyveld et al. [11]	<200	0.35 (0.22–0.55)	0.46 (0.30–0.70)
Kaplan et al. [12]	>500	1	3.1 (1.4–6.6)
Kawado et al. [13]	≥500	1	1.36 (0.45–4.16)
Lifson et al. [14]	≥500	1	1.29 (0.71–2.35)
Cain et al. [15]	>500	1	*1.14 (1.07–1.22)