Diagnosis and Treatment of Childhood Pulmonary Tuberculosis: A Cross-Sectional Study of Practices among Paediatricians in Private Sector, Mumbai
Table 4
Comparison of anti-tubercular regimens prescribed for new patients by paediatricians in private sector with standard guidelines.
Regimens prescribed for new pulmonary TB by paediatricians in private sector
Number (%) ()
Is prescription recommended by ISTC 2009?
Is prescription recommended by IAP?
2 HRZE + 4 HR#
38 (61.4)
Recommended
Recommended
2 HRZ + 4 HR
15 (24.2)
Not recommended
Recommended
2 HRZ + 7 HR
2 (3.2)
Not recommended
Recommended
2 HRZE + 4 HRE
2 (3.2)
Not recommended
Partial
HRZ + E
3 (4.8)
Not recommended
Not recommended
HRZES
2 (3.2)
Not recommended
Not recommended
Dosage (mg/kg)
Number (%)
H = 5 ()
22 (44.9)
Lower dose
✓
H = 10
26 (53.1)
✓
✓
H = 15
1 (2.0)
✓
Higher dose
R = 10 ()
47 (95.9)
✓
✓
R = 15
2 (4.1)
✓
Higher dose
Z = 15–25 ()
32 (68.1)
Lower dose
Lower dose
Z = 30–35
13 (27.7)
✓
✓
Z = 35–40
2 (4.3)
✓
Higher dose
E = 15–20 ()
14 (35)
✓
✓
E = 25
26 (65)
✓
Higher dose
S = 15–20 ()
2 (66.7)
Not recommended
✓
S = 21–40
1 (33.3)
Not recommended
Higher dose
ISTC—International Standard for tuberculosis care, IAP—Indian academy of paediatricians, Suggested dosages from ISTC 2009 page 37 (Original source: WHO. Treatment of tuberculosis: guidelines—4th ed. WHO/HTM/TB/2009. 420 World Health Organisation, Geneva, 2009). Drug Code: H = Isoniazid, R = Rifampicin, Z = Pyrazinamide, E = Ethambutol, S = Streptomycin. ✓ indicates that dose prescribed is in line with recommendations of ISTC or IAP, #regimen as per ISTC standard.
