Impact of HIV Infection and Zidovudine Therapy on RBC Parameters and Urine Methylmalonic Acid Levels

Table 2

Comparing mean values of Hb, MCV, RDW, UMMA, BMI, and CD4 parameters among study groups by ANOVA.

Parameters	Control	Naïve	Zt	NZt	value
	Hb (g/dL)	12.80	11.40	10.10		11.70	0.008
MCV (fL)	82.90	85.90	93.00	97.40	0.001
RDW-SD (fL)	43.50	50.60	58.50	55.80	0.028
UMMA (mg/24 hrs)	2.85	40.00	10.20	7.70	0.001
BMI (kg/m^2)	25.4	24.68	22.92	23.03	0.377
CD4 (cells/µL)	306	304	261	310	0.613

UMMA, urine methylmalonic acid; MCV, mean cell volume; RDW, red cell distribution width; Hb, haemoglobin concentration; BMI, body mass index; CD4, cluster of differentiation 4; naïve, HIV positive treatment naïve subjects; Zt, zidovudine based treatment group; NZt, non-zidovudine-based treatment group. value (significant level for ANOVA statistics). Post hoc statistics: show significant mean difference in ZT versus NZt group for Hb, MCV, and RDW-SD ().