Prevalence, Characteristics, and One-Year Follow-Up of Congenital Cytomegalovirus Infection in Isfahan City, Iran

Table 1

Maternal and neonatal characteristics in infant with congenital Cytomegalovirus infection.

Case number	1	2	3	4	5	6	7	8
Gender	Female	Female	Male	Female	Female	Male	Male	Female
Gestation age (week)	39	39	38	39	38	35	35	38
Birth weight (g)	2950	2610	3140	2520	2650	2600	2700	3180
Birth weight for age (-score)	−0.63	−1.45	−0.43	−1.68	−1.35	0.25	0.49	−0.11
Birth height (cm)	48	49	50	45	46	49	49	48.0
Birth head circumference (cm)	35	32	34	33.5	33	33.5	33.6	32.5
Birth head circumference for age (-score)	0.95	−1.59	−0.36	−0.32	−0.74	1.06	1.12	−1.59
Reason for hospitalization at first week of life	—	—	—	Jaundice at birth, normal LFT	—	Jaundice, RDS	Poor feeding	—
Maternal comorbidities	None	None	None	None	None	GDM, anemia	GDM, anemia	None
Urine CMV DNA (copies/ml)	146	149775	1057	239541	535	39850	3565302	7095
Abnormal physical examination (from 6 months afterward)	Palpable spleen	—	—	—	Palpable spleen	—	—	—
Abnormal laboratory results (initial)	—	—		Neutropenia	—	Neutropenia	—	—
Abnormal laboratory results (at 1 year of age)		—	Neutropenia	—	—	—	—	—
Cranial ultrasound	Subependymal fine calcification	Normal	Ventricular calcification	Normal	Focal subependymal calcification	Normal	Normal	Normal
Brain CT scan	Normal	—	Normal	—	Normal	—	—	—
Audiometry (initial and at 1 year of age)	Normal	Normal	Normal	Normal	Normal	Normal	Normal	Mild
Ophthalmologic examination	Hyperpigmentation of retinal pigment epithelium	Normal	Normal	Normal	Normal	Normal	Normal	Normal
Antiviral therapy	—	—	—	—	—	—	—	—

CMV: Cytomegalovirus; GDM: gestational diabetes mellitus; LFT: liver function test; RDS: respiratory distress syndrome; SNHL: sensory neural hearing loss.
a: defined as absolute neutrophil count 500–1000/mm³; b: defined as platelet count less than 150000/mm³; c: defined as hearing threshold 26–40 dBHL.