Interdisciplinary Perspectives on Infectious Diseases / 2019 / Article / Tab 5

Research Article

Assessing the Impact of Isoniazid Preventive Therapy (IPT) on Tuberculosis Incidence and Predictors of Tuberculosis among Adult Patients Enrolled on ART in Nekemte Town, Western Ethiopia: A Retrospective Cohort Study

Table 5

Effect of IPT on reduction of tuberculosis incidence among cohorts of PLWHA at Nekemte referral hospital and Nekemte Health center followed from September 2009-September 2012.

IPT adjusted covariatesUnadjusted hazard 95%CIp-valueAdjusted Hazard 95 %CIp-valueSignificant reduction in TB (%)p-value for interaction

IPT0.397(0.203- 0.774)0.0070.449(0.219-0.920)¥0.02955¥

IPT∗
Cotrimoxazole
0.402(0.206-0.784)0.007600.219

IPT∗
WHO stage
0.382(0.196-0.745)0.005620.48

IPT∗
CD4 count
0.348(0.176-0.685)0.002650.64

IPT∗
Functional status
0.386(0.198-0.754)0.005610.08

IPT∗
BMI
0.403(0.206-0.788)0.012600.072

IPT∗
Weight
0.426(0.218-0.831)0.008570.74

IPT∗
Sex
0.399(0.204-0.778)0.007400.85

IPT∗
opportunistic infection
0.396(0.203-0.773)0.007600.61

IPT∗
age
0.403(0.206-0.788)0.008600.065

IPT∗ previous TB0.401(0.205-0.785)0.008600.588

IPT adjusted for each covariate.
¥Overall effect of IPT adjusted for all covariates.

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