Research Article

Current Practice and Barriers to an Early Antimicrobial Conversion from Intravenous to Oral among Hospitalized Patients at Jimma University Specialized Hospital: Prospective Observational Study

Table 3

Intravenous to oral antimicrobial therapy conversion outcomes at Jimma University Specialized Hospital, South West Ethiopia, February–September, 2014.

Variable Implementation

Duration of IV therapy
 all patients
  mean± SD 7.66 ± 3.25 (n=142)
  median; range7; 0 – 15
 converted patients
  mean± SD3.30 ± 2.26 (n=20)
 non-converted patients
  mean± SD8.64 ± 2.70 (n=44)

Time to clinical stability (days )
 all patients
  mean± SD6.04± 3.25 (n=136)
  median; range5;0 – 16
 converted patients
  mean± SD3.40± 2.37 (n=20)
 non-converted patients
  mean± SD8.69± 3.73(n=44)

Observation period after conversion (days )
  mean± SD5.18± 4.60 (n=28)
  median; range4.5;0 – 15

Duration of IV therapy after clinical stability for non-converted patients (days)
  mean ±SD3.23± 2.09 (n=44)
  median; range3; 0 – 8

Number of IV antimicrobial prescriptions for which duration was specified (n=total number of prescriptions)7(n=174)

Length of hospital stay (days)
 all patients
  mean± SD13.42 ± 7.89(n=142)
  median; range11; 1 – 44
 converted patients
  mean± SD9.0 ± 5.23 (n=20)
 non-converted patients
  mean± SD13.45 ± 5.48 (n=44)

Total antibiotic acquisition costs (birr)24495.04
Cost saving analysis
Total amount saved
 Converted groups3074.84 (n=20)
 Non-converted groups 4080.06 (n= 44)