Daclatasvir and Sofosbuvir Therapy Enhance Monocyte Phenotypic Changes in Naive Chronic Hepatitis C Patients: A Prospective Cohort Study

Figure 1

Flow-cytometer analysis of peripheral blood monocyte subsets: (a) isotopic control; (b) monocytes were assessed using an SSC/CD14 dot plot; (c) monocytes (R1) back-gated within the FCS/SSC dot plot; (d) the monocyte subsets within the (R1) population were assessed according to the expression of CD14/CD16; the three monocyte subsets were defined as classical CD14++CD16+ (R2), intermediate CD14+CD16+ (R3), and nonclassical CD14+/-CD16++ (R4) and small negative population for CD14-/CD16-, likely representing dendritic cells; (e) median fluorescence intensities (MFI) of CD14 and CD16; (f) MFI of CD16.

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