Effects of Lysozyme, Proteinase K, and Cephalosporins on Biofilm Formation by Clinical Isolates of Pseudomonas aeruginosa

Table 3

Biofilm reduction (%) at different concentrations of lysozyme and proteinase K.

Isolate code	Lysozyme concentration (μg/mL)			Proteinase K concentration (μg/mL)
	5	10	30	2	5	10
B3	16.9	18.1	18.4	3.5	20.2	8.8
Cl3	17.5	25.8	30.6	1.3^#	2.5^#	4.2^#
E4	25.8	34.3	44.8	2.5^#	1.3^#	3.3^#
U7	8.7	10.4	12.9	53.4	69.8	55.4
U16	0.8	0.9	1.5	33.2	26.9	41.8
U19	5.1	6.5	7.4	10.4	10.2	5.6
W10	10.5	11.2	12	5.2^#	6.1^#	7.3^#
W12	3.4	6.9	8.2	15.4	15.4	15.4
W14	28.2	30	35.9	28	30.5	15.9
Average ± SE	12.9 ± 1.08	16±	19±
1.29	19 ± 1.63	1.29	1.63

^#Enhancement of biofilm formation indicated as%. The percent biofilm reduction or enhancement for each isolate was determined after normalization to negative controls, which were not treated with the enzymes; averages are the means ± standard errors (SEs) of the means from four independent experiments. B: burn; Cl: contact lens; E: eye; U: urine; W: wound.