Research Article

The Presence of Antineutrophil Cytoplasmic Antibodies and Antiphospholipid Antibodies in Patients with Severe Acute Respiratory Syndrome Coronavirus 2: A Case-Control Study among Sudanese Patients

Table 1

Baseline sociodemographic characteristics of cases and controls.

CharacteristicsTotal N (%)Cases N (%)Controls N (%) value (χ2)

Age (mean±SD)43 ± 16.544.2 ± 17.541.9 ± 15.50.194a
10-193 (3.3)1 (2.2)2 (4.4)0.76 (3.4)
20–2922 (24.2)12 (26.1)10 (22.)
30–3916 (17.6)7 (15.2)9 (20)
40–4918 (19.8)8 (17.4)10 (22.2)
50–5914 (15.4)6 (13)8 (17.8)
60–607 (7.7)5 (10.9)2 (4.4)
>7011 (12.1)7 (15.2)4 (8.9)

Gender
Male64 (70.3)35 (78.3)28 (62.2)0.09 (2.8)
Female27 (29.7)10 (21.7)17 (37.8)

Address
Urban78 (85.7)40 (89.1)37 (82.2)0.35 (0.89)
Rural13 (14.3)5 (10.9)8 (17.8)

Level of education
No formal education16 (17.6)8 (17.4)8 (17.8)0.98 (0.15)
Primary15 (16.5)7 (15.2)8 (17.8)
Secondary13 (14.3)7 (15.2)6 (13.3)
University47 (51.6)23 (52.2)23 (51.1)

Chronic illness
Diabetes mellitus30 (33)29 (65.2)<0.001 (43.7)
Hypertension2 (2.2)2 (4.3)0.16 (2)
Asthma5 (5.5)1 (2.2)4 (8.9)0.16 (1.9)
Seizure disorder1 (1.1)1 (2.2)0.32 (0.98)
Renal impairment2 (2.2)1 (2.2)1 (2.2)0.99 (0)
Tuberculosis4 (4.4)3 (6.5)1 (2.2)0.32 (1)
SLE1 (1.1)1 (2.2)0.32 (0.99)

Final outcome
Recovered86 (94.5)40 (89.1)45 (100)0.023 (5.2)
Dead5 (10.9)5 (5.5)

Immunoglobulin’s profile
IgM, positive5 (10)
IgG, positive13 (28)
IgA, positive8 (17.4)

Superscript a: independent samples t-test. Abbreviations: IgA/G/M, immunoglobulins; SLE, systemic lupus erythematosus. Comparisons of proportions were performed using the chi-square χ2 or Fisher’s exact test.