Changing Patterns in the Clinical Pathological Features of Hodgkin Lymphoma: A Report from Debrecen, Hungary

Table 2

Hungarian trials dealing with HL patients.

Author	Investigated period	Number of HL patients	Male/female ratio	Mean ages (years)	Most common histological subtype (%)	Age group pattern	B symptoms (%)	Early stages (%)	Advanced stages (%)
István and Giczy, 1979 [13]	1953–1974	166	1.81 : 1	Unknown	Unknown	Bimodal (15–40 and 50–65 years)	Unknown	Unknown	Unknown
Kelényi and Várbiró, 1980 [14]	1978	69	0.97 : 1	41.7	MC 45%	Bimodal (20–30 and 50–70 years)	Unknown	Unknown	Unknown
Iványi et al., 1988 [15]	1975–1986	66	0.88 : 1	35.8	MC 36.36%	Unknown	54.54%	34.80%	65.20%
Fleischmann, 1985 [16]	1978–1985	167	Unknown	Unknown	Unknown	Unknown	60%	16.90%	83.10%
Berényi et al., 1989 [17]	1983–1987	233	1.53 : 1	Unknown	MC 43.8%	Bimodal (10–20 and 40–60 years)	56.70%	41.60%	58.40%
Endrédi et al., 1991[18]	1987–1988	202	1.15 : 1	39.5	MC 42.6%	Unknown	Unknown	Unknown	Unknown
Illés et al., 1998 [19]	1975–1997	473	1.46 : 1	Unknown	MC 43.2%	Unimodal (20–30 years)	53.30%	33.30%	66.70%
Illés et al., 2004 [20]	2000–2003	611	1.27 : 1	39.6	NS 44%	Unimodal (20–30 years)	51.00%	66.00%	34.00%
Simon et al., 2007 [12]	1995–2004	163	0.96 : 1	36	MC 48.5%	Bimodal (20–30 and 50–60 years)	51.00%	41.10%	58.90%
Miltényi, Illés et al., 2008	1980–1989	177	1.42 : 1	40.1	MC 43.7%	Unimodal (30–40 years)	51.60%	33%	67%
Miltényi, Illés et al., 2008	1990–1999	147	1.45 : 1	35.9	MC 58.23%	Bimodal (20–30 and 40-50 years)	50.90%	31%	69%
Miltényi, Illés et al., 2008	2000–2008	115	1.04 : 1	36.8	MC 42.6%	Bimodal (20–30 and 50–60 years)	50.80%	59.12%	40%