Genotyping of CYP2D6 Polymorphisms by MALDI-TOF Mass Spectrometry in Sardinian People
Figure 2
In (a) a Cluster plot for 1661G>C SNP is shown. Homozygous wild type G/G samples are displayed in (α), homozygous mutate C/C samples in (β) and heterozygous G/C samples in (γ); in (δ) and (ε) are displayed outlier samples resulting in gene copy number variation [5]; (ζ) negative control (H2Odd). In (b) a Mass Spectra for the detection of 1661G>C in a heterozygous G/C sample, displayed in (a) position (γ). In (c) a Mass Spectra for the detection of 1661G>C in the outlier sample, displayed in (a) position (δ), and resulting in allele [5]. In (d) Mass Spectra for the detection of 1661G > C in an outlier sample, displayed in (a) position (ε), and resulting in allele [5].
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