International Scholarly Research Notices / 2013 / Article / Fig 3

Research Article

Genotyping of CYP2D6 Polymorphisms by MALDI-TOF Mass Spectrometry in Sardinian People

Figure 3

MALDI-TOF MS cluster plot distribution for 3176C>T [17] and 3948G>T [18] newly discovered SNPs [5]. In each cluster, there are visualized 32 samples presenting heterozygous status for −1584G>C SNP and submitted to both types of PCR analysis, LongRange PCR (Section 2, paragraph 1) and the two single allele PCR (Section 2, paragraph 2), for a total of 96 PCR analyses. (a) Cluster plot for 3176C>T SNP. (α) homozygous wild type C/C samples; (β) one out of the two heterozygous C/T samples presenting heterozygous status for −1584G>C SNP also; (γ) the same heterozygous sample analysed in single allele PCR; (ζ) negative control ( ). (b) Cluster plot for 3948T>G SNP. (α) homozygous wild type T/T samples; (β) the only heterozygous T/G sample; (γ) the only heterozygous sample analysed in single allele PCR; (ζ) negative control ( ).
609797.fig.003a
(a)
609797.fig.003b
(b)

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