International Scholarly Research Notices / 2014 / Article / Tab 3

Research Article

Altered Metabolic Profile in Congenital Lung Lesions Revealed by 1H Nuclear Magnetic Resonance Spectroscopy

Table 3

Metabolites ratio in lung neonatal tissues. The first three ratios are obtained by 1H 1D NMR results reported in Table 2. The PCho/GPCho ratio is derived from 1H-1H 2D NMR analysis: diagnostic cross peak heights of PCho and GPCho are compared to give a semiquantitative estimate of their relative concentration. Ratios and associated confidence limits are derived as reported in Experimental Section.

Metabolites ratioBroncho pulmonary sequestrationBronchogenic cystCongenital lobar emphysemaControl lung

1D NMR1D NMR1D NMR1D NMR
Lac/Glc62.5 ± 0.53.91 ± 0.0210.48 ± 0.073.87 ± 0.04
Lac/Creat18.1 ± 0.211.9 ± 0.0719.0 ± 0.124.2 ± 0.2
Myo/Glc23.5 ± 0.11.44 ± 0.014.21 ± 0.020.457 ± 0.003

2D  NMR2D  NMR2D  NMR2D  NMR
PCho/GPCho5.6 ± 0.50.96 ± 0.047.0 ± 0.20.41 ± 0.02

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