Review Article

Pharmacological and Ethnomedicinal Overview of Heritiera fomes: Future Prospects

Table 3

Observed pharmacological activity of H. fomes in various test methods with different solvent extractions.

Solvent extraction and plant part(s) testedObserved activityTest methodReferences

EtOH extracts of leaves.Antinociceptive Hot plate, acetic acid-induced writhings in mice [25]
Antioxidant DPPH radical scavenging assay
Antimicrobial Disk diffusion assay

80% EtOH crude, CHCll3, EtOAc, BuOH, aqueous residue extracts of stem bark, and pure compoundsAntioxidant15-Lipoxygenase inhibition, total phenolic content, and DPPH radical scavenging assay [12]
80% EtOH crude, CHCl3, EtOAc, BuOH, aqueous residue, precipitate extracts of stem bark, and negative control (acetone, MeOH)AntimicrobialAgar disc diffusion method

MeOH extract of barkAntihyperglycemicLowering serum glucose level in hyperglycemic mice following of glucose loading [11]
AntinociceptiveAcetic-acid-induced writhings in mice

MeOH extract of both leaf and stem powderAnticancer activity In vitro cell viability and In vivo screening assay against B16 mouse melanoma and EAC (ehrlich ascites carcinoma) in mice model [13]
chromatography characterizationTLC (qualitative and quantitative DPPH assay), HPLC, 1H NMR, FTIR spectral analysis, and bioautography screening

EtOH extracts of pneumatophores Comparative antibacterial activityMinimum Inhibitory Concentration (MIC) method [54]