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Journal of Addiction
Volume 2017, Article ID 6748948, 6 pages
Research Article

A Prototypical First-Generation Electronic Cigarette Does Not Reduce Reports of Tobacco Urges or Withdrawal Symptoms among Cigarette Smokers

1Department of Psychology, University of Kentucky, Lexington, KY, USA
2Department of Psychiatry, University of Kentucky, Lexington, KY, USA
3Department of Biostatistics, University of Kentucky, Lexington, KY, USA
4Department of Behavioral Science, University of Kentucky, Lexington, KY, USA

Correspondence should be addressed to Arit M. Harvanko; ude.yku@h.tira

Received 14 December 2016; Revised 21 February 2017; Accepted 6 March 2017; Published 26 March 2017

Academic Editor: Elisardo Becona

Copyright © 2017 Arit M. Harvanko et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


It is unknown whether first-generation electronic cigarettes reduce smoking urges and withdrawal symptoms following a 24 h deprivation period. This study tested whether a first-generation electronic cigarette reduces smoking urges and withdrawal symptoms in cigarette smokers. Following 24 h of tobacco deprivation, using a within-subjects design, eight nontreatment seeking tobacco cigarette smokers (3 females) administered 10 puffs from a conventional cigarette or a first-generation electronic cigarette containing liquid with 0, 8 or 16 mg/ml nicotine. Conventional cigarettes ameliorated smoking urges and electronic cigarettes did not, regardless of nicotine concentration. First-generation electronic cigarettes may not effectively substitute for conventional cigarettes in reducing smoking urges, regardless of nicotine concentration.