Qualitative and Computational Analysis of a Mathematical Model for Tumor-Immune Interactions
The phase spaces at different equilibria where stable steady states [•], unstable steady states [○], stable manifold [- - -], unstable manifold [⋯], and initial conditions [+], exist. (with immunotherapy with both ACI and IL-2, see Table 1 and , .).
(a) Tumor-free equilibrium ( and )
(b) One persistent-tumor equilibrium with a stable limit cycle ( and )
(c) One persistent-tumor equilibrium at little ( and )
(d) One persistent-tumor equilibrium ( and )
(e) Three persistent-tumor equilibria with a stable limit cycle ( and )
(f) Three persistent-tumor equilibria ( and )
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