B. Gouget, Y. Gourmelin, A. Feuillu, F. Blanchet, B. Capolaghi, M. Lagente, G. Lardet, J. C. Manceaux, A. Truchaud, "Assessment of recently developed blood gas analysers: a multicentre evaluation", Journal of Analytical Methods in Chemistry, vol. 11, Article ID 876159, 7 pages, 1989. https://doi.org/10.1155/S1463924689000519
Assessment of recently developed blood gas analysers: a multicentre evaluation
Providing guidelines for testing expected inaccuracy and imprecision is still a matter under debate. The Expert Panel of the French Society of Clinical Chemistry has developed a protocol, which was based on a comparative multi-centre evaluation of four instruments: the Ciba-Corning 278, the Instrumentation Laboratory 1306, the Nova SP 5 and the ABL 330. The purpose was to evaluate the analytical performance and efficiency of the analysers. Another aim was to design a valid approach for evaluating any new system. As buffered aqueous solutions and fluorocarbon emulsions give only partial information, tonometered blood was used at different levels of gas mixture, even though it is both difficult and time-consuming. Comparisons have been established on patients' blood samples with the analysers currently used in the evaluation sites. The tests showed that the four analysers have the same degree of precision, and interinstrument comparisons demonstrated a very high degree of reliability.This analysis emphasizes that the evaluation of instruments for pH and blood gas analysis is neither easy nor is it often done, mainly due to the choice of a quality-control material and the lability of the measured parameters.
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