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Journal of Automatic Chemistry
Volume 12 (1990), Issue 1, Pages 17-21

Correlation of fasting blood glucose and haemoglobin A1c measured with an automated analyser

1Department of Clinical and Laboratory Medicine, Osaka City University Medical School, Asahimachi 1-5-7, Abeno-ku, Osaka 545, Japan
2Midori Health Care Foundation, Tarumicho 3-22, Suita 565, Japan

Copyright © 1990 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A subtype of glycohaemoglobin, haemoglobin (Hb) A1c, in specimens of whole blood was assayed on a new automated analyser that makes use of high-pressure liquid chromatography. The analyser provided precise and reproducible values. The mean of the HbA1c values was lower than that with an older instrument. The mean tended to increase with the age of the subjects, who were undergoing routine health examinations. No sex difference was found. When measurement was made 1 h after the subjects drank 50g of glucose, the value of HbA1c was unaffected. Correlation was strong between the HbA1c value and the fasting blood glucose value, which suggested that fasting blood glucose could be estimated from the HbA1c value.