New Automated and High-Throughput Quantitative Analysis of Urinary Ketones by Multifiber Exchange-Solid Phase Microextraction Coupled to Fast Gas Chromatography/Negative Chemical-Electron Ionization/Mass Spectrometry

Table 2

Summary of the method performance.

	Range	Slope	Intercepts	LOD
	(mg/L)	(m)	(b)	(mg/L)
BOHB-methylester (EI, quantification ion m/z 43)	10–500	0.00122±0.000014	0.000403±0.000153	0.49
Ace-PFBHA-oxime (NCI, quantification ion m/z 178)	0.1–10	0.106050±0.000679	0.002073±0.000778	0.0294
MEK-PFBHA-oxime (NCI, quantification ion m/z 178)	0.025–4.0	0.28966±0.003915	0.00084±0.00009	0.0033
MIBK-PFBHA-oxime (NCI, quantification ion m/z 178)	0.2–4.0	0.186707±0.002173	0.00058±0.000128	0.004
Chone-PFBHA-oxime (NCI, quantification ion m/z 178)	0.05–4.0	0.320697±0.006647	0.000757±0.00021	0.0032
2,5 HD bis-PFBHA-oxime (NCI, quantification ion m/z 178)	0.01–1.0	0.34784±0.007879	0.001147±0.000423	0.0049
AcAc-methylester-PFBHA-oxime (NCI, quantification ion m/z 178)	0.5–50	0.024497±0.000948	0.002573±0.001285	0.1755
BOHB-TBDMS (EI, quantification ion m/z 275)	250–1000	0.000193±0.000005	0.007547±0.000638	43.46
AcAc-TBDMS (EI, quantification ion m/z 273)	250–1000	0.00035±0.000016	0.00434±0.000979	16.15