Bioanalytical Method Development and Validation of Memantine in Human Plasma by High Performance Liquid Chromatography with Tandem Mass Spectrometry: Application to Bioequivalence Study

Table 5

Pharmacokinetic parameters of memantine after administration of 10 mg of test and reference products in 20 healthy human volunteers.

Pharmacokinetic parameters	𝐶max (T/R)	AUC0−𝑡 (T/R)	AUC0−∞ (T/R)
Test/Ref	99.72	103.06	107.89