Research Article

Simultaneous Analysis of Losartan Potassium, Amlodipine Besylate, and Hydrochlorothiazide in Bulk and in Tablets by High-Performance Thin Layer Chromatography with UV-Absorption Densitometry

Table 1

Results from assay of losartan potassium, amlodipine besylate, and hydrochlorothiazide in Trilopace*H tablets.

ComponentLabel claim (mg)Amount found (mg ± SD, 𝑛 = 3 )Percentage of label claim (±SD)

Losartan potassium50 4 9 . 5 1 ± 0 . 3 3 0 9 9 . 0 3 ± 0 . 6 6 5
Amlodipine besylate5 4 . 8 6 ± 0 . 0 5 7 9 8 . 4 7 ± 1 . 1 1 4
Hydrochlorothiazide12.5 1 2 . 4 ± 0 . 0 3 6 9 9 . 2 2 ± 0 . 2 8 4