Thermoanalytical Investigation of Some Sulfone-Containing Drugs

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr class="thead"><td align="left">Drug</td><td align="center">Temperature range (°C)</td><td align="center">Order of reaction</td><td align="center"><svg height="14.35" id="M13" style="vertical-align:-3.22281pt" version="1.1" viewbox="0 0 16.762501 14.35" width="16.762501" xmlns="http://www.w3.org/2000/svg">
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<text transform="matrix(1,0,0,-1,-71.95,63.79)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝐸</tspan>
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<text transform="matrix(1,0,0,-1,-63.02,60.66)">
<tspan style="font-size: 8.75px; " x="0" y="0">a</tspan>
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</svg> (KJ moL<sup>−1</sup>)<svg height="0.125" id="M14" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 5.3375001 0.125" width="5.3375001" xmlns="http://www.w3.org/2000/svg">
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</svg></td><td align="center"><span style="width: 36.512501px;"><svg height="10.8" id="M15" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 36.512501 10.8" width="36.512501" xmlns="http://www.w3.org/2000/svg">
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<g transform="translate(72,-63.36)">
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<tspan style="font-size: 12.50px; " x="0" y="0">l</tspan>
<tspan style="font-size: 12.50px; " x="3.4758339" y="0">n</tspan>
<tspan style="font-size: 12.50px; " x="15.966331" y="0">𝐴</tspan>
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<g transform="translate(72,-63.74)">
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</svg></span></td></tr><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr><td align="left">Dapsone</td><td align="center">339–393</td><td align="center">1</td><td align="center">485.87</td><td align="center">88.255</td><td align="left">0.9921</td></tr><tr><td align="left">Topiramate</td><td align="center">151–393</td><td align="center">1</td><td align="center">93.78</td><td align="center">13.993</td><td align="left">0.9957</td></tr><tr><td align="left">Dimethyl sulfone</td><td align="center">170–299</td><td align="center">zero</td><td align="center">51.006</td><td align="center">11.815</td><td align="left">0.9903</td></tr><tr class="table-tr"><td colspan="6"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Kinetic parameters from the Arrhenius equation for Dapsone, Topiramate, and dimethyl sulfone.

Journal of Analytical Methods in Chemistry

Thermoanalytical Investigation of Some Sulfone-Containing Drugs

Table 2