Journal of Analytical Methods in Chemistry / 2012 / Article / Tab 6 / Research Article
Sensitive Spectrophotometric Determination of Atenolol in Pharmaceutical Formulations Using Bromate-Bromide Mixture as an Eco-Friendly Brominating Agent Table 6 Results of recovery study by standard addition method.
Tablets Method A Method B Method C ATN in tablets,
𝜇
g/mL Pure ATN
𝜇
g/mL Total
𝜇
g/mL Pure ATN ATN in
𝜇
g/mL Pure ATN
𝜇
g/mL Total
𝜇
g/mL Pure ATN ATN in
𝜇
g/mL Pure ATN
𝜇
g/mL Total found,
𝜇
g/mL Pure ATN Atenex 25 4.08 2.0 6.07
9
9
.
5
±
2
.
2
9
7.97 4.0 12.01
1
0
1
.
0
0
±
2
.
7
4
2.02 1.0 3.05
1
0
3
.
0
0
±
1
.
7
6
4.08 4.0 8.03
9
8
.
7
5
±
2
.
7
9
7.97 8.0 15.93
9
9
.
5
0
±
2
.
3
5
2.02 2.0 4.09
1
0
3
.
5
±
1
.
9
8
4.08 6.0 10.15
1
0
1
.
1
7
±
1
.
2
2
7.97 12.0 20.10
1
0
1
.
0
8
±
0
.
9
8
2.02 3.0 5.11
1
0
3
.
0
0
±
1
.
5
2
Atekind 50 3.99 2.0 6.06
1
0
3
.
5
±
1
.
9
1
8.05 4.0 12.16
1
0
2
.
7
5
±
2
.
1
5
1.99 1.0 3.00
1
0
1
.
0
0
±
0
.
9
7
3.99 4.0 8.14
1
0
3
.
7
5
±
1
.
0
4
8.05 8.0 16.15
1
0
1
.
2
5
±
2
.
7
6
1.99 2.0 4.02
1
0
1
.
5
0
±
1
.
5
8
3.99 6.0 10.23
1
0
4
.
0
0
±
2
.
5
1
8.05 12.0 20.44
1
0
3
.
2
5
±
2
.
4
0
1.99 3.0 5.03
1
0
1
.
3
3
±
1
.
7
9
Aten 100 4.02 2.0 6.10
1
0
4
.
0
0
±
2
.
3
1
8.09 4.0 12.18
1
0
2
.
2
5
±
1
.
5
6
1.99 1.0 3.02
1
0
3
.
0
0
±
2
.
1
3
4.02 4.0 8.16
1
0
3
.
5
±
1
.
4
3
8.09 8.0 16.35
1
0
3
.
2
5
±
2
.
4
5
1.99 2.0 4.05
1
0
3
.
0
0
±
2
.
0
6
4.02 6.0 10.29
1
0
4
.
5
±
2
.
7
7
8.09 12.0 20.34
1
0
2
.
0
8
±
1
.
4
7
1.99 3.0 5.07
1
0
2
.
6
7
±
1
.
9
1
*Mean value of three determinations.
