Research Article

Stability Studies of Thiocolchicoside in Bulk and Capsules Using RP-HPTLC/Densitometry

Table 4

Forced degradation studies.

Stress conditionsTemperature % Recovery ( )
Thiocolchicosidepeak-1peak-2peak-3

1.0 M HCl60°C 78.00 (0.60)8.22 (0.33)13.78 (0.71)
0.5 M NaOH60°C 85 (0.60) 15 (0.72)
1% v/v H2O2RT 67.50 (0.60)2.18 (0.38)10.20 (0.46)20.12 (0.70)
Photodegradation-day light (8 h/day)RT 92.94 (0.60)
Dry heat 70°C 98.12 (0.60)

RT: Room Temperature.