Research Article
Stability Studies of Thiocolchicoside in Bulk and Capsules Using RP-HPTLC/Densitometry
Table 4
Forced degradation studies.
| Stress conditions | Temperature | % Recovery () | Thiocolchicoside | peak-1 | peak-2 | peak-3 |
| 1.0 M HCl | 60°C | 78.00 (0.60) | 8.22 (0.33) | 13.78 (0.71) | | 0.5 M NaOH | 60°C | 85 (0.60) | 15 (0.72) | — | — | 1% v/v H2O2 | RT | 67.50 (0.60) | 2.18 (0.38) | 10.20 (0.46) | 20.12 (0.70) | Photodegradation-day light (8 h/day) | RT | 92.94 (0.60) | — | — | — | Dry heat | 70°C | 98.12 (0.60) | — | — | — |
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RT: Room Temperature.
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