Journal of Analytical Methods in Chemistry / 2013 / Article / Tab 7

Research Article

Application of a Stability-Indicating HPTLC Method for Simultaneous Quantitative Determination of Olmesartan Medoxomil and Hydrochlorothiazide in Pharmaceutical Dosage Forms

Table 7

Comparison of the proposed method with the reported HPLC method.

ParameterHPLCHPTLC
OLM HTZOLMHTZ

Linearity4–24  g/mL2.5–15  g/mL80–480 ng/band25–150 ng/band
LOD0.44  g/mL0.21  g/mL18.12 ng/band6.31 ng/band
LOQ1.32  g/mL0.63  g/mL56.35 ng/band18.56 ng/band
Tablet analysis (% recovery)100.24100.10103.0399.08

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