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Journal of Analytical Methods in Chemistry
Volume 2013 (2013), Article ID 380705, 6 pages
http://dx.doi.org/10.1155/2013/380705
Research Article

Headspace Single-Drop Microextraction Gas Chromatography Mass Spectrometry for the Analysis of Volatile Compounds from Herba Asari

1National Institutes for Food and Drug Control, No. 2, Tiantan Xili, Beijing 100050, China
2Beijing Institute of Technology, No. 5, Zhongguancun South Street, Haidian District, Beijing 100081, China

Received 7 January 2013; Revised 18 February 2013; Accepted 5 March 2013

Academic Editor: Shuang-Qing Zhang

Copyright © 2013 Guan-Jie Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A rapid headspace single-drop microextraction gas chromatography mass spectrometry (SDME-GC-MS) for the analysis of the volatile compounds in Herba Asari was developed in this study. The extraction solvent, extraction temperature and time, sample amount, and particle size were optimized. A mixed solvent of n-tridecane and butyl acetate (1 : 1) was finally used for the extraction with sample amount of 0.750 g and 100-mesh particle size at 70°C for 15 min. Under the determined conditions, the pound samples of Herba Asari were directly applied for the analysis. The result showed that SDME-GC–MS method was a simple, effective, and inexpensive way to measure the volatile compounds in Herba Asari and could be used for the analysis of volatile compounds in Chinese medicine.