A Sensitive and Selective Method for Determination of Aesculin in Cortex Fraxini by Liquid Chromatography Quadrupole Time-of-Flight Tandem Mass Spectrometry and Application in Pharmacokinetic Study

Table 2

Linearity for assay of aesculin in rat plasma.

Analytical batch	Slope	Intercept	Regression equation	Correlation coefficient
1	0.0365	0.0332	𝑦=0.0365𝑥+0.0332	𝑟=0.9902
2	0.0384	0.0341	𝑦=0.0384𝑥+0.0341	𝑟=0.9915
3	0.0352	0.0337	𝑦=0.0352𝑥+0.0337	𝑟=0.9946
4	0.0379	0.0354	𝑦=0.0379𝑥+0.0354	𝑟=0.9952
5	0.0369	0.0327	𝑦=0.0369𝑥+0.0327	𝑟=0.9929