Alkaloids in Processed Rhizoma Corydalis and Crude Rhizoma Corydalis Analyzed by GC/MS

Table 1

Alkaloids identified from processed RC and RC by mass spectrum.

Peaks	Retention time	Compounds	Match degree	Sample source
1	20.288	4b,5,10,10a,11,-12-Hexahydro-3-hydroxy-2,8,9-tri(methoxy) Isoquino [2.1-b] isoquinoline	90	②
2	25.771	N-Methyllaurotetanine	81	②
3	26.158	Glaucine	78
4	26.420	(+)-Corydaline 178 355 369	—	②, ③
5	26.485	(+)-Corydaline 178  369	—	①
6	26.668	(13S.13aR)-2,3-Dioxhydryl-9,13-methyl-10-ethyl-6,8.13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline; ==H,  =CH3,  =C2H5,   =CH3 192, 355	—	②
7	26.936	(13S.13aR)-2,3-(Methylenedioxy)-9,10-dimethoxy-13-methyl-; 6,8.13,13a-tetrahydro-5H-isoquinolino2,1-bisoquinoline; + =–CH2–,  ===CH3  178 355	—	②
8	27.076	(+)-Canadine C20H21O4N	76	③
9	27.425	Protopine	90	③
10	27.468	6H-Dibenzoa,gquinolizine, 5,8,13,13a-tetrahydro-2,3,10,11-tetramethoxy; ====CH3,  =H 164, 192 355	84	②, ③
11	27.741	6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-; tetramethoxy; ====CH3,  =H 164, 192 355	83	②, ③
12	28.257	Isoquino [2.1-b] isoquinoline, 4b,5,10,10a,11,12-hexahydro-2- hydroxy-3,8,9-trismethoxy-C20H23O4N 341	92	②, ③
13	29.041	Isocorydine C20H23O4N 341	64	②

“—”: identified by artificial analysis.
Sample source: ① the processed Rhizoma Corydalis sample extracted with methanol, ② the crude Rhizoma Corydalis sample extracted with methanol, and ③ the crude Rhizoma Corydalis sample extracted with acetone.