Spectrophotometric Determination of Gemifloxacin Mesylate, Moxifloxacin Hydrochloride, and Enrofloxacin in Pharmaceutical Formulations Using Acid Dyes
Table 2
Intraday and interday precision and accuracy data for GMF obtained by the proposed methods.
Method
Added (μg mL−1)
Intraday
Interday
Recovery %
Precision RSD %a
Accuracy RE %
Confidence limitb
Recovery %
Precision RSD %a
Accuracy RE %
Confidence limitb
BCG
5.0
99.30
0.53
−0.80
4.996 ± 0.026
100.60
0.43
0.60
5.03 ± 0.022
10
99.50
0.65
−0.50
9.950 ± 0.065
99.30
0.59
−0.70
9.930 ± 0.059
15
99.10
0.82
−0.90
14.865 ± 0.122
99.90
0.83
−0.10
14.985 ± 0.124
BCP
4.0
100.60
0.47
0.60
4.024 ± 0.019
99.30
0.51
−0.70
3.988 ± 0.02
8.0
99.20
0.72
−0.80
7.936 ± 0.057
99.70
0.70
−0.30
7.976 ± 0.056
12
100.20
1.17
0.20
12.024 ± 0.141
100.30
1.10
0.30
12.036 ± 0.132
BPB
5.0
100.10
0.49
0.10
5.005 ± 0.025
99.60
0.62
−0.40
4.98 ± 0.031
10
99.80
0.79
−0.20
9.98 ± 0.079
99.40
0.87
−0.60
9.94 ± 0.086
15
99.70
1.01
−0.30
14.955 ± 0.151
100.20
1.24
0.20
15.03 ± 0.23
BTB
5.0
99.60
0.65
−0.40
4.98 ± 0.032
99.70
0.54
−0.30
4.985 ± 0.027
10
100.10
0.88
0.10
10.01 ± 0.088
99.30
0.75
−0.70
9.93 ± 0.074
15
100.40
0.93
0.40
15.06 ± 0.140
100.20
1.08
0.20
15.03 ± 0.162
MO
10
99.60
0.44
−0.40
9.96 ± 0.044
99.50
0.52
−0.50
9.95 ± 0.052
20
99.80
0.68
−0.20
19.96 ± 0.136
99.70
0.83
−0.30
19.94 ± 0.166
30
100.30
0.98
0.30
30.09 ± 0.295
100.20
1.20
0.20
30.06 ± 0.361
Mean of six determinations; RSD %: percentage relative standard deviation; RE %: percentage relative error. Confidence limit at 95% confidence level and five degrees of freedom ().
